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Mastering ImmunityProImmune’s mission is to be your partner of choice for understanding and managing adaptive immune responses. We offer unique solutions for preclinical and clinical immunology research, including a comprehensive and integrated antigen characterization platform, and products and services for tracking antigen-specific immune responses with state-of-the-art ELISpot and flow cytometry techniques. We are committed to helping you take your studies to success through product innovation, responsive service and focused application support, saving you time and money and reducing risk. The Story of ProImmune...The study of immunology isn’t only relevant to illness. Every foreign agent that enters the body has the potential to provoke a response from the immune system. Usually, this keeps us disease-free, as ‘self’ is tolerated and ‘non-self’ attacked and eliminated. When ‘self’ is mistakenly attacked, we see the development of autoimmune disease, and when ‘non-self’ gets the upper hand we fall prey to acute or chronic infections. Researchers developing vaccines seek to enhance the immune response to pathogens to prime the body’s own arsenal against future infections. On the flip side, every drug and even every food, cosmetic or other household additive can potentially generate unwanted immune responses and nobody wants to be allergic to their shampoo or breakfast cereal. Everyone from medical researchers to household brands needs to know exactly which substances can stimulate the immune system, and which substances can sneak under the radar. Portions of substances that the immune system can recognise are called epitopes, and identifying potential epitopes and monitoring the immune response to them is where ProImmune has become a world leader.
ProImmune has pro-actively maintained links with its academic roots and contributed to diverse collaborative projects such as Allostem (a European transplant research initiative), AutoCure (autoimmune disease research) and VITAL (exploring non-Hodgkins lymphoma treatments). The company’s motto ‘Mastering Immunity’ reflects the importance to medical science of understanding how the immune system functions. Infectious diseases (eg HIV, Hepatitis, Influenza), cancer, allergies, debilitating autoimmune diseases (eg Rheumatoid Arthritis), and neurodegenerative diseases (eg Multiple Sclerosis), could in principle all be prevented and cured by a correctly functioning immune system. Understanding immunity and how to manage it is key to preventing and curing these diseases and presents an enormous opportunity to address global, unmet medical needs. To that end, ProImmune offers clients the opportunity to save time by outsourcing aspects of their research programmes or clinical trials. Over the years the company has developed a unique expertise in tracking immune responses and custom epitope-discovery services, which are vital to groups involved in clinical studies on the immune system. Most recently ProImmune has launched a range of services to predict potential adverse reactions to drugs and vaccines before they are first trialled on people. Nik Schwabe says: “We try to mimic and predict the function of the immune system in laboratory tests that rely on donated human samples, such as blood and serum, in a way that can also reduce, and in some cases eliminate, the need for animal testing. Our goal is that eventually every drug and vaccine that comes to market anywhere in the world will have been evaluated for potential and actual immune responses with groundbreaking new methods.” ProImmune employs around 50 people and sells its products and services directly to most countries of the world, with exports accounting for more than 85% of its business. Linda and Nikolai have created a highly-skilled team of scientists with a strong focus on research and development, ensuring that the company continues to offer innovative products and services that address the needs of medical researchers. As a result the company now counts most of the world's leading pharmaceutical and biotechnology companies, as well as several thousand academic groups, among its regular customers. Directors and ManagementDr Nikolai Schwabe
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