Customer Research Highlights
Our customers continually publish their research into a huge range of
subjects. Here we present selected case studies and editorials, highlighting
different applications of our technologies, from epitope discovery to
vaccine development, and combined with techniques such as magnetic
separation and intracellular staining.

Click here for a comprehensive list of customer publications, which we update frequently.
Synopses of customer research into the following areas are presented below

Allergy
Katharina Steinitz, Baxter, Austria What
causes adverse reactions to Factor VIII treatment?
Julio Delgado, University of Utah
The Who How and Why of Seafood Allergy, using ProImmune’s Antigen Characterization Platform
T cell Assays for Allergenicity Testing: How do Functionally Similar Proteins Compare in their Immunogenicity?
Autoimmunity
Dolores Jaraquemada, Universitat Autònoma de Barcelona
Grave's Disease Peptides are Characterized using ProImmune Class II REVEAL Binding Assay
Damien Bresson, LIAI
Research Into Type I Diabetes Therapy Makes use of PEPscreen® Technology
Terrance O'Hanlon, National Institute of Environmental Health
Sciences
Invited Editorial: Epitope Discovery for
Inflammatory Myopathy Treatment
More Autoimmunity
Publications Citing ProImmune
Cancer
Immunovaccine Inc, Nova Scotia, Canada
Liposomes deliver an immune hit
to cancer cells
Marcus Butler, Dana Farber Cancer Centre
Killer T Cells Trained for Long-lasting Anti-Cancer Effects
John Webb, British Columbia Cancer Agency
High-grade Ovarian Cancer: MHC Pentamers are Used to Investigate Immunotherapy Prospects
Maxim Pavlenko, Karolinska University Hospital
Epitope Discovery in Prostate Cancer: Characterizing an Immunodominant CTL Epitope of PSA in Mice
Vincenzo Cerullo, University of Helsinki
First Ever Tumor-specific Response Observed for Human Patients in Oncolytic Adenovirus Cancer Gene Therapy Study
James Wells, King's College London
New Adjuvant Drives Unprecedented Cytotoxic T Cell Response Providing a Potent Vaccine Development Platform
Hiro Yagi, Hamamatsu University School of Medicine
Pro5® Pentamers Integral in Successful Research Into Novel Immunization Strategy
Norman Woller, Edkulla Ramakrishna, Medizinische Hochschule Hannover
Using thinkpeptides to Improve Virotherapy Against Tumor Targets
More Cancer Publications Citing ProImmune
EBV
Stephanie Gras, Queensland Institute of Medical Research
Analyzing Allelic Polymorphism in the T Cell Receptor and its Impact on Immune Responses in an EBV Setting
Judy Tellam, Queensland Institute of Medical Research
Pro5® MHC Class I Pentamer Combined with Intracellular
Cytokine Staining Shows How Protein Translation Affects the Molecular Dynamics of Antigen Presentation
John J. Miles, Cardiff University School of Medicine, Cardiff
Invited Editorial: Tracking the TCR
Repertoire Evolution During Primary Viral Infection in Humans
More EBV publications citing ProImmune
Hepatitis (HBV and HCV)
Adam Gehring, Singapore Institute for Clinical Science
Phenotypic Analysis of HBV-specific T Cells Using Pro5® Pentamers
Victoria Kasprowicz, University of KwaZulu Natal
A Story of Viral Escape Through Sequence Variation in Chronic Hepatitis C Virus Infection
Lars Frelin, Karolinska Institute
Developing a Therapeutic Hepatitis B Vaccine with Pro5® Pentamers
Eleanor Barnes, University of Oxford
Success for Hepatitis C Vaccine Trials at Oxford University
Tanja Lange, University of Lübeck
Sleep Your Way to Better Immunity - Sleep
After Vaccination Boosts Immunological Memory
More Hepatitis Publications Citing ProImmune
HIV
Samantha Westrop, Chelsea & Westminster Hospital
ProImmune REVEAL & ProVE® Rapid Epitope Discovery System used to Identify Novel T Cell Epitopes in HIV-1
Jorge Almeida, INSERM
T Cell Vaccines for HIV-1 Move a Step Closer - Researchers
Use HIV-specific Pro5® MHC Class I Pentamers Combined with Intracellular Cytokine Staining
Aude Chapuis, Fred Hutchinson Cancer Research Center, USA
Sending in Trained Killers to Attack Residual HIV Infection
University of Manitoba Researchers Use PEPscreen® Library for Epitope Mapping
Tarmo Mölder, University of Tartu
HIV Vaccine Study in Pigs Uses PEPscreen® Peptides in ELISpot Assays
More HIV Publications Citing ProImmune
Influenza
J Guo, University of Texas, USA
Deletion of FoxN1 in the thymic medullary epithelium reduces peripheral T cell responses to
infection and mimics changes of aging
Roberto Mallone, Hôpital Saint Vincent de Paul
How Does Blood Processing Affect the Results of Cell Mediated Immunity Assays?
ProImmune's Flu Pro5® MHC Class I Pentamer is Used as an Exemplar in an Exploratory Study
Suryaprakash Sambhara, Centre for Disease Control and Prevention CDC
Study on H5N1 Vaccine Uses Pro5® Pentamer to Correlate Immune Response with Protection
More Influenza Publications Citing ProImmune
NKT Cells and CD1d
Thierry Mallevaey, INSERM
NKT Cells are Important in the Acquired Immune Response During Helminthiasis
Omar Duramad, Regimmune
ProImmune’s Human CD1d Tetramer Detects NKT Cells from Non-human Primates
More Publications Citing ProImmune CD1d Tetramers
Other Viral diseases
Defence Science and Technology Laboratories, UK The Human Side of Counter-Bioterrorism: T
Cell Proliferation Assays Validate Humanization of an anti-VEEV Antibody
Gene Olinger, USAMRIID
ProImmune’s Antigen Characterization Platform Accelerates Development of a Vaccine for Ebola and Marburg Viruses
Giovanna Rappocciolo, University of Pittsburgh
ProImmune’s REVEAL & ProVE® Rapid Epitope Discovery System
Validates Novel Epitopes Important for CD8+ T Cell Control of Human Herpesvirus 8
Andre Oliveira, University College Dublin
ProImmune REVEAL and ProVE® Used to Identify First HTLV-2 MHC Class I Epitope
Pim van der Heiden, Leiden University Medical Center
Discovery of First VZV HLA-A2 Epitope, Using ProImmune REVEAL & ProVE® Technology
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