ProImmune Pre-Mixed Peptide Pools

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ProMix Pre-Mixed, Purified Peptide Pools

ProMix peptide pools from thinkpeptides consist of a select number of peptides representing the key immunodominant epitopes from a specific protein or pathogen, providing a comprehensive picture of the T cell response. Peptide selection is based on well-established and published epitopes with a wide range of HLA restrictions covering the most relevant HLA types in the population.

 

Key advantages of ProMixes:

  • ProMix peptide pools use well characterized epitopes to provide a representative picture of the T cell response against a protein or disease.
  • Smaller numbers of peptides in each pool are designed to elicit a targeted response based on immunodominant epitopes.
  • Uniform >95% purity in pools.
  • Peptide pool content is clearly defined, allowing individual peptide responses to be mapped easily if this is required.
  • Highly efficient and cost effective method for classifying T cell response.
Image: HIV gag p17&p24 protein complex

HIV-1 gag p17/p24 with three epitopes from the HIV ProMix® peptide pool mapped to its surface.

 

Research Areas

Cancer

ProMix™ Number of peptides Code
ProMix™ NY-ESO-1 Peptide Pool 5 PX-NYESO
ProMix™ Prostate Specific Antigen Peptide Pool 9 PX-PSA
ProMix™ Survivin Peptide Pool 11 PX-SURV
ProMix™ bcr/c-abl Peptide Pool 6 PX-BCR
ProMix™ Telomerase Reverse Transcriptase Peptide Pool 12 PX-TERT
ProMix™ Prostate Specific Membrane Antigen Peptide Pool 7 PX-PSMA
ProMix™ gp100/p-mel Peptide Pool 8 PX-GP100
ProMix™ Tyrosinase Peptide Pool 6 PX-TYR

 

Infectious Diseases

ProMix™ Number of peptides Code
ProMix™ Adenovirus Peptide Pool 5 PX-ADENO
ProMix™ CMV Peptide Pool 14 PX-CMV
ProMix™ EBV Peptide Pool 26 PX-EBV
ProMix™ Influenza Peptide Pool 17 PX-FLU
ProMix™ Hepatitis C Virus Peptide Pool 21 PX-HCV
ProMix™ Hepatitis B Virus Peptide Pool 9 PX-HBV
ProMix™ HIV Peptide Pool 22 PX-HIV
ProMix™ Human Papillomavirus Peptide Pool 14 PX-HPV
ProMix™ CEFT Peptide Pool 24 PX-CEFT
ProMix™ CEF Peptide Pool 32 PX-CEF
ProMix™ Respiratory Syncytial Virus Peptide Pool 28 PX-RSV

 

 

In most cases we aim to achieve coverage for the most common HLA types, and where applicable other alleles that may be of particular relevance with the disease or protein of interest.

With ProMix peptide pools, the pooling procedure is done for you, with the peptides guaranteed >95% pure. Each ProMix pool contains 25μg of each peptide and is available for dispatch within 1-2 days.

HLA-A HLA-B
A*01:01 B*07:02
A*02:01 B*08:01
A*03:01 B*35:01
A*24:02 B*27:05
A*11:01 B*44:03
A*68:01 B*57:01
B*51:01

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thinkpeptides is a brand of ProImmune