Our customers continually publish their research into a huge range of subjects. Here we present selected case studies and editorials, highlighting different applications of our technologies, from epitope discovery to vaccine development, and combined with techniques such as magnetic separation and intracellular staining.
Synopses of customer research into the following areas are presented below:
Katharina Steinitz, Baxter, Austria What causes adverse reactions to Factor VIII treatment?
Julio Delgado, University of Utah The Who How and Why of Seafood Allergy, using ProImmune’s Antigen Characterization Platform
T cell Assays for Allergenicity Testing: How do Functionally Similar Proteins Compare in their Immunogenicity?
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Dolores Jaraquemada, Universitat Autònoma de Barcelona Grave’s Disease Peptides are Characterized using ProImmune Class II REVEAL Binding Assay
Lena Israelsson, Karolinska Institute Defining Autoantibody Binding to Citrullinated Target Proteins in Rheumatoid Arthritis using Peptide Arrays
Kaare Engkilde, University of Copenhagen Mouse CD1d Tetramers Used to Correlate NKT Cell Activity with Protection from Type 1 Diabetes
Damien Bresson, LIAI Research Into Type I Diabetes Therapy Makes use of PEPscreen® Technology
Terrance O’Hanlon, National Institute of Environmental Health Sciences Invited Editorial: Epitope Discovery for Inflammatory Myopathy Treatment
More Autoimmunity Publications Citing ProImmune
Immunovaccine Inc, Nova Scotia, Canada Liposomes deliver an immune hit to cancer cells
Marcus Butler, Dana Farber Cancer Centre Killer T Cells Trained for Long-lasting Anti-Cancer Effects
John Webb, British Columbia Cancer Agency High-grade Ovarian Cancer: MHC Pentamers are Used to Investigate Immunotherapy Prospects
Erlend Stronen, Radiumhospitalet Oslo Pentamers Identify Allo-restricted T Cells in Study to Advance Research Into Cancer Immunotherapy
Richard Harrop, Oxford Biomedica Novel Epitope Detection in Phase II Trial for Colorectal Cancer
Maxim Pavlenko, Karolinska University Hospital Epitope Discovery in Prostate Cancer: Characterizing an Immunodominant CTL Epitope of PSA in Mice
Vincenzo Cerullo, University of Helsinki First Ever Tumor-specific Response Observed for Human Patients in Oncolytic Adenovirus Cancer Gene Therapy Study
James Wells, King’s College London New Adjuvant Drives Unprecedented Cytotoxic T Cell Response Providing a Potent Vaccine Development Platform
Hiro Yagi, Hamamatsu University School of Medicine Pro5® Pentamers Integral in Successful Research Into Novel Immunization Strategy
Norman Woller, Edkulla Ramakrishna, Medizinische Hochschule Hannover Using thinkpeptides to Improve Virotherapy Against Tumor Targets
More Cancer Publications Citing ProImmune
Daniela Weiskopf, Austrian Academy of Sciences ProImmune REVEAL® Rate assays and Pro5® Pentamers Central to Study Investigating Oxidative Stress
Paul Moss, University of Birmingham Pro5® Pentamers are Used to Enrich CMV-specific T Cells for Transfusion Into Transplant Patients
More CMV Publications Citing ProImmune
Stephanie Gras, Queensland Institute of Medical Research Analyzing Allelic Polymorphism in the T Cell Receptor and its Impact on Immune Responses in an EBV Setting
Judy Tellam, Queensland Institute of Medical Research Pro5® MHC Class I Pentamer Combined with Intracellular Cytokine Staining Shows How Protein Translation Affects the Molecular Dynamics of Antigen Presentation
Michael Uhlin, Karolinska Institute Pro5® Pentamers Central in Life-saving Procedure for PTLD Treatment
Michael Uhlin, Karolinska Institute Invited Editorial: The Best Strategy for Adoptive T Cell Transfer
Suzanne Elliot, Queensland Institute of Medical Research Pro5® MHC Class I Pentamers Used to Evaluate Vaccine Safety
John J. Miles, Cardiff University School of Medicine Invited Editorial: Tracking the TCR Repertoire Evolution During Primary Viral Infection in Humans
More EBV publications citing ProImmune
Gouri Pandey, FDA ProImmune REVEAL® Class II HLA-Peptide Binding Assay used to identify potential potential FVIII epitopes that increase the risk of FVIII inhibitors in African-American Haemophilia A patients compared with Caucasians
Katherine High, The Children’s Hospital of Philadelphia Pro5® MHC Pentamers used in conjunction with ProPresent® Antigen Presentation Assays to identify MHC class I epitopes in AAV vectors that trigger cytotoxic T cell responses when presented by hepatocytes
Adam Gehring, Singapore Institute for Clinical Science Phenotypic Analysis of HBV-specific T Cells Using Pro5® Pentamers
Victoria Kasprowicz, University of KwaZulu Natal A Story of Viral Escape Through Sequence Variation in Chronic Hepatitis C Virus Infection
Lars Frelin, Karolinska Institute Developing a Therapeutic Hepatitis B Vaccine with Pro5® Pentamers
Eleanor Barnes, University of Oxford Success for Hepatitis C Vaccine Trials at Oxford University
Tanja Lange, University of Lübeck Sleep Your Way to Better Immunity – Sleep After Vaccination Boosts Immunological Memory
More Hepatitis Publications Citing ProImmune
Samantha Westrop, Chelsea & Westminster Hospital ProImmune REVEAL & ProVE® Rapid Epitope Discovery System used to Identify Novel T Cell Epitopes in HIV-1
Jorge Almeida, INSERM T Cell Vaccines for HIV-1 Move a Step Closer – Researchers Use HIV-specific Pro5® MHC Class I Pentamers Combined with Intracellular Cytokine Staining
Aude Chapuis, Fred Hutchinson Cancer Research Center, USA Sending in Trained Killers to Attack Residual HIV Infection
University of Manitoba Researchers Use PEPscreen® Library for Epitope Mapping
Tarmo Mölder, University of Tartu HIV Vaccine Study in Pigs Uses PEPscreen® Peptides in ELISpot Assays
More HIV Publications Citing ProImmune
Sanja Selak, Intercell AG Developing Effective Vaccine Strategies for Complex Pathogens
Maziar Divangahi, Harvard Medical School, USA A Messy End for TB-infected Macrophages
Ana Ferreira, Instituto Gulbekian de Ciência, Portugal Researchers Show How Inheritance of Sickle Cell Anemia Protects Against Malaria Infection
Virginie Roupie, Scientific Institute of Public Health, Brussels PEPscreen® Used in Vaccine Development for Mycobacterium Tuberculosis
Cyrille Bisseye, Medical Research Council UK and The Gambia Designing a Malaria Vaccine
J Guo, University of Texas Deletion of FoxN1 in the thymic medullary epithelium reduces peripheral T cell responses to infection and mimics changes of aging
Roberto Mallone, Hôpital Saint Vincent de Paul How Does Blood Processing Affect the Results of Cell Mediated Immunity Assays? ProImmune’s Flu Pro5® MHC Class I Pentamer is Used as an Exemplar in an Exploratory Study
Sohail Ahmed, Novartis ProImmune REVEAL® MHC Peptide Binding Assays used by team at Novartis and Stanford University to investigate immunological insights into the causation of narcolepsy associated with pandemic H1N1 influenza vaccine Pandemrix®
More Influenza Publications Citing ProImmune
Stefan Porubsky, DKFZ The Significance of Isoglobotrihexosylceramide (iGb3) as the Natural CD1d Ligand in Mice
Maya Fedeli, H San Raffaele Scientific Institute NKT Cell Differentiation Depends on Dicer Processing of MicroRNA
Thierry Mallevaey, INSERM NKT Cells are Important in the Acquired Immune Response During Helminthiasis
Omar Duramad, Regimmune ProImmune’s Human CD1d Tetramer Detects NKT Cells from Non-human Primates
More Publications Citing ProImmune CD1d Tetramers
Defence Science and Technology Laboratories, UK The Human Side of Counter-Bioterrorism: T Cell Proliferation Assays Validate Humanization of an anti-VEEV Antibody
Gene Olinger, USAMRIID ProImmune’s Antigen Characterization Platform Accelerates Development of a Vaccine for Ebola and Marburg Viruses
Giovanna Rappocciolo, University of Pittsburgh ProImmune’s REVEAL & ProVE® Rapid Epitope Discovery System Validates Novel Epitopes Important for CD8+ T Cell Control of Human Herpesvirus 8
Andre Oliveira, University College Dublin ProImmune REVEAL and ProVE® Used to Identify First HTLV-2 MHC Class I Epitope
Pim van der Heiden, Leiden University Medical Center Discovery of First VZV HLA-A2 Epitope, Using ProImmune REVEAL & ProVE® Technology